Tmem63a是什么

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August undefined, 2024

WebCell ID: IDG-HEK293T-TMEM63A-V5-OE. Selection: Blasticidin to a final concentration of 10μg/m. Organism: Homo sapiens, human. Description: This cell line stably expresses … WebImmunocytochemistry/ Immunofluorescence - Anti-TMEM63A antibody (ab221878) PFA-fixed, Triton X-100 permeabilized RT4 (Human bladder transitional-cell carcinoma cell line) cells stained for TMEM63A (green) using ab221878 at 4 ug/ml in ICC/IF. Protocols. Immunocytochemistry & immunofluorescence protocols.

A novel de novo TMEM63A variant in a patient with severe ...

WebJul 12, 2024 · Introduction. Amputation per se is a severe physical and psychological traumatic event with a high incidence worldwide. In addition, up to 70%–80% of patients with amputation experience severe chronic post-amputation pain (CPAP), which can be devastating [1, 2].CPAP is a long-lasting and severe pain after amputation surgery … WebStrikingly, TMEM63A in turn stabilizes oncoprotein DERL1 through preventing TOLLIP-mediated autophagic degradation. Notably, pharmacological inhibition of VCP by CB-5083 or knockdown of DERL1 partially abolishes the oncogenic effects of TMEM63A on TNBC progression both in vitro and in vivo. Collectively, these findings uncover a previously ... imthecode

Mechanosensitive Ion Channel TMEM63A Gangs Up with Local …

WebHuman diseases caused by Tmem63a mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER. Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes. Human diseases associated with … WebIDG-HEK293T-TMEM63A-V5-OE. Selection: Blasticidin to a final concentration of 10μg/m. Organism: Homo sapiens, human. Description: This cell line stably expresses dark ion channel in frame with V5 tag on the C-terminus. The ion channel construct is randomly integrated in the genome using lentiviral transduction. This cell line also expresses ... WebNov 8, 2016 · TMEM63A. transmembrane protein 63A. Gene ID: 9725, updated on 8-Dec-2024. Gene type: protein coding. Also known as: HLD19; KIAA0792. See all available tests … im the crazy one

Tmem63a MGI Mouse Gene Detail - MGI:2384789

Single cell type - TMEM63A - The Human Protein Atlas

WebKJ892838 - Synthetic construct Homo sapiens clone ccsbBroadEn_02232 TMEM63A gene, encodes complete protein. AB383993 - Synthetic construct DNA, clone: pF1KSDA0792, Homo sapiens TMEM63A gene for transmembrane protein 63A, complete cds, without stop codon, in Flexi system. AK093860 - Homo sapiens cDNA FLJ36541 fis, clone … WebTmem63a. Name. transmembrane protein 63a. Synonyms. MGC:11687, MGC:25803. Feature Type. protein coding gene. IDs. MGI:2384789. im the chosen one sWebExome sequencing of the patient and her parents revealed a novel de novo missense variant, NM_014698.3:c.1658G>T, p.(Gly553Val), in the TMEM63A gene, which was confirmed by … im the code

"WebNov 8, 2016 · Spinal cord involvement and paroxysmal events in "Infantile Onset Transient Hypomyelination" due to TMEM63A mutation. The N- and C-terminal carbohydrate recognition domains of Haemonchus contortus galectin bind to distinct receptors of goat PBMC and contribute differently to its immunomodulatory functions in host-parasite … " - Tmem63a是什么

Tmem63a是什么

Transmembrane protein 63A is a partner protein of …

WebMar 21, 2024 · TMEM63A (Transmembrane Protein 63A) is a Protein Coding gene. Diseases associated with TMEM63A include Leukodystrophy, Hypomyelinating, 19, Transient … WebImmunofluorescence showed that TMEM63A was localized to the cell membrane. Flow cytometric analysis revealed that TMEM63A was expressed in the majority of goat PBMCs. After using RNA interference to knockdown expression of TMEM63A, the PBMC proliferation and migration were significantly increased, while the influence of rHco-gal-m on

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WebPrimePCR™ PreAmp for SYBR® Green Assay: Tmem63a, Mouse Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis. List Price: $159.00 Your Price: Log In Quantity: Add to Cart ... WebFeb 1, 2024 · We found a de novo variant in TMEM63A (NM_014698.3:c.1658G>T, p.(Gly553Val)), which was validated by Sanger sequencing (Fig. 2 A). This variant …

http://www.pibb.ac.cn/pibbcn/article/html/20240421 WebThis is a rabbit polyclonal antibody against TMEM63A and was validated on Western blot. Theoretical MW. 89 kDa. Disclaimer note: The observed molecular weight of the protein …

WebApr 9, 2015 · The localization of transmembrane protein 63A (TMEM63A) in peripheral blood mononuclear cells (PBMCs) was detected by immunofluorescence. The distribution of TMEM63A in T cells, B cells and monocytes in PBMCs was detected by flow cytometry. The immunomodulatory effects of Hco-gal-m and TMEM63A on cell proliferation, migration, … WebTMEM63A is part of cluster 8 Oligodendrocytes - Myelin sheath organization with confidence i Confidence is the fraction of times a gene was assigned to the cluster in …

WebCo-expression of mouse TMEM63A, TMEM63B and TMEM63C confers hyperosmolarity activated ion currents in HEK293 cells. Osmoreception is essential for systemic osmoregulation, a process to stabilize the tonicity and volume of the extracellular fluid through regulating the ingestive behaviour, sympathetic outflow and renal function.

WebJul 31, 2024 · TMEM63A, TYR559HIS. RCV002271995. In a 15-month-old girl with hypomyelinating leukodystrophy-19 (HLD19; 618688 ), Tonduti et al. (2024) identified a de … im the cleaning ladyWebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. TMEM63A INFORMATION. Proteini. Full gene name according to HGNC. Transmembrane protein … im the cleverWebAug 7, 2024 · Zhao et al. (2016) cloned mouse Tmem63a (), Tmem63b, and Tmem63c (), which are orthologs of the Arabidopsis hyperosmolarity-activated ion channels Csc1 and Osca1. Wu et al. (2024) identified 4 isoforms of mouse Tmem63b resulting from adenosine-to-inosine editing that changed glutamine (Q) to arginine (R) in exon 20 and alternative … im the creature from under someone elses bedTransmembrane protein 63A is a protein that in humans is encoded by the TMEM63A gene. The mature human protein is approximately 92.1 kilodaltons (kDa), with a relatively high conservation of mass in orthologs. The protein contains eleven transmembrane domains and is inserted into the membrane of … See more Overview TMEM63A is located on the negative DNA strand of chromosome 1 at location 1q42.12, spanning base pairs 226,033,237 to 226,070,069. Aliases include KIAA0489 and KIAA0792. The … See more Properties and characteristics The mature form of the human TMEM63A protein has 807 amino acid residues with an isoelectric point of 6.925. This is fairly conserved across … See more • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): … See more Paralogs TMEM63A has two paralogs: TMEM63B, which is located at 6p21.1, and TMEM63C, which is located at C14orf171. Alignment between them shows that TMEM63C is more closely related to TMEM63B than TMEM63A. A BLAST … See more lithonia 2blt 2x4WebCatalog #. AM16708. Standard 5 nmol. Purification: HPLC In-Vivo Ready Standard. Size: 5 nmol 20 nmol 20 nmol 20 nmol 20 nmol 40 nmol 40 nmol 100 nmol 250 nmol 250 nmol 1 … lithonia 2blt4 30lWebApr 9, 2015 · Our results show that TMEM63A is a binding partner of Hco-gal-m/f, and involved in the immune responses of host PBMCs induced by Hco-gal-m for the first time. Hco-gal-m and -f were two isoforms of galectin cloned from male and female Haemonchus contortus, respectively, and it was demonstrated that recombinant Hco-gal-m and -f could … lithonia 2blt4 40l adp ez1 lp835WebAug 3, 2024 · Here, we report for the first time that TMEM63A (transmembrane protein 63A), a poorly characterized TMEM protein with unknown functions in human cancer, functions as a novel oncogene to promote ... lithonia 2blt2r