Phospho sting antibody
WebSTING (stimulator of interferon genes) is encoded by the TMEM173 gene and is an adaptor molecule involved in the activation of innate immune responses to PAMPS (pathogen … WebPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / …
Phospho sting antibody
Did you know?
WebJan 29, 2015 · To rule out any nonspecific staining by the phospho-specific antibody, we used proximity ligation assay (PLA) in L929-hSTING-Flag cells (Fig. S8H), where positive … WebPhospho-STING-Ser366 polyclonal antibody (Stimulator of interferon genes protein) binds to endogenous Stimulator of interferon genes protein only when phosphorylated at Ser366. Phosphorylation by TBK1 leads to activation and production of IFN-beta. Following cyclic nucleotide (c-di-GMP or cGAMP)-binding, activation and translocation from the ...
WebPhospho-STING (Ser365) Antibody (PA5-117271) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser365) Polyclonal Antibody (Product # PA5-117271). … WebInvitrogen Anti-Phospho-STING (Ser366) Polyclonal, Catalog # PA5-105674. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and …
WebSTING (TMEM173), also called stimulator of interferon genes, is a transmembrane adaptor protein that plays an important role in the innate immune response against viral and bacterial infections. It has been shown that cyclic GMP-AMP synthase (cGAS) plays a key role in STING activation. WebThe Phospho-STING (Ser366) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. The first antibody is selected for its specific binding to the phosphorylated motif on the protein, the second for its ability to recognize the protein independent of its phosphorylation state.
WebCell Signaling Technology's Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) is a Rabbit monoclonal antibody. The Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with …
WebWestern blot analysis of THP-1, using Phospho-STING/TMEM173-S366 antibody (AP1223) at 1:600 dilution.THP-1 cells were transfection with poly (dA:dT) (5ug/mL) for 3 hours. Secondary antibody: HRP Goat Anti-Rabbit … the price is right templateWebSTING agonism enhances anti-tumor immune responses and therapeutic efficacy of PARP inhibition in BRCA-associated breast cancer. View PDF In NPJ Breast Cancer on 6 September 2024 by Pantelidou, C., Jadhav, H., et al.. Applications: WB Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration. … sigh toneWebFor Analyzing Cell Signaling Pathway Activation. Phosphorylation, the addition of a phosphate group to serine, threonine or tyrosine residues, is an important cellular process utilized to send cellular signals from the membrane to the nucleus. For example, changes in physiological conditions may require immediate changes in gene expression. the price is right temptation gallery wikiWebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. Alias: Fold/Unfold the price is right tampa flhttp://www.biodragon.cn/plus/pdf.php?aid=116632 the price is right take two gallery fandomWebInhibition of IDH3α enhanced the efficacy of chemoimmunotherapy by activating cGAS-STING pathway through regulating acidic tumor microenvironments. Preprint on Research Square on 11 October 2024 by Zhang, L., Dai, X., et al.. sight oneWebSep 30, 2024 · A polyclonal antibody against phospho-S365 of mouse STING was generated in rabbits and affinity-purified (Fig. S2E). Polyclonal antibodies against mouse STING, Igα, Igβ, class I MHC heavy chain ... sight one landscape